Conferences, accessible research notes, and the progress of ongoing publications.
Presentation of the PMCHS/SIDS hypothesis to clinicians and researchers specialized in neuro-inflammatory diseases and immunopathology. Four degranulation phenotypes, SIDS signal (9.7%), vagal tone, archaic reflexes and neonatal GIH as converging mechanistic pathways.
📄 Download the one-pagerPoster accepted for presentation at ISMCAS 2027 (Minnesota). Confirmation received from Laurie Radovsky.
Millions of people live with conditions"of unknown cause". This note explains why mast cells could be the missing link, and what the word"programmed" changes about how we understand these illnesses.
Read the note →9.7% of survey respondents report a family history of sudden infant death. This note explores the possible link between mast cell hyperreactivity and SIDS, and argues for formal investigation.
Read the note →Lipedema affects about 11% of women and is almost systematically misdiagnosed. This note describes how mast cell inflammation, amplified by estrogen, creates pathological adipose tissue resistant to conventional approaches.
Read the note →Some forms of obesity don't respond to classic approaches because they're driven by mast cell inflammation of adipose tissue. This note explains the mechanism and its therapeutic implications within the PMCHS terrain.
Read the note →Unexplained palpitations, orthostatic intolerance, or a cardiac reaction during an allergy episode can share the same origin: cardiac mast cells too easily activated.
Read the note →Bronchodilator-resistant asthma, apnea without obvious excess weight, unexplained bronchospasms — these presentations can stem from bronchial and laryngeal mast cell activation.
Read the note →These three chronic skin conditions share a central mechanism: local mast cell activation amplified by stress, hormones, and certain foods.
Read the note →Some psychiatric presentations don't respond to classic antidepressants because they're partly sustained by mast cell neuro-inflammation.
Read the note →"Functional" colic affects 20 to 40% of infants. This note explains the post-prandial mast cell mechanism and what the maternal PMCHS terrain changes about the equation.
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